BY Fraser Tennant
Building upon its existing immunology pipeline, Belgian biopharmaceutical group UCB is to acquire Candid Therapeutics, a privately-held clinical-stage biotechnology company, in a transaction valued at up to $2.2bn
Under the terms of the definitive agreement, UCB will pay $2bn upfront and up to $200m in potential future milestone payments for the California-headquartered Candid – a deal that swiftly follows UCB’s acquisition of clinical-stage Asia-Pacific biopharmaceutical company Antengene in March 2026.
Reflecting a platform-driven strategy in next generation immunology, UCB’s investments expand its reach across multiple B cell targets and disease mechanisms, strengthening its ability to address antibody mediated autoimmune diseases through differentiated, biology driven approaches rather than reliance on a single asset or modality.
“This acquisition demonstrates our inorganic innovation strategy in action and marks a pivotal moment for UCB, as we secure a significant technological advancement in the field with the addition of cizutamig to our pipeline,” said Jean-Christophe Tellier, chief executive of UCB. “This exemplifies the next wave of therapies to treat immune mediated diseases and reflects our commitment to setting new standards to achieve immune reset.”
Clinically evaluated in over 100 patients with multiple myeloma and autoimmune diseases, cizutamig – an investigational drug that has not been approved by the Food and Drug Administration or other health authorities – is currently in multiple clinical studies in over 10 autoimmune indications.
“We consider cizutamig as a potential transformative asset,” continued Mr Tellier. “It complements our existing programmes, and is poised to redefine treatment expectations for severe, underserved immune-mediated diseases, offering the potential to deliver meaningful improvements in patient outcomes and quality of life.”
In addition to cizutamig, Candid is developing a differentiated pipeline of multispecific T-cell engagers (TCEs) designed to enable deep, targeted depletion of pathogenic B cell populations in immune mediated diseases to achieve immune reset.
“We purposefully built a broad portfolio of TCE assets against a number of clinical indications,” said Ken Song, chairman, chief executive and president of Candid Therapeutics. “Our focus has been to efficiently generate clinical data so as to identify where our TCEs could provide maximal clinical benefit for the broadest number of patients.”
The transaction is subject to certain closing conditions, including required antitrust clearance and other customary conditions, and is expected to close by end of the second quarter or early in the third of 2026.
Mr Song concluded: “UCB’s successful track record in immunology, including development, launch and commercialisation, will enable the continuation of Candid’s clinical programmes and help deliver on the potential for our pipeline.”
News: Belgian pharma group UCB to buy Candid Therapeutics for up to $2.2 billion